BAV-299
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 100mg | In Stock | 500 |
| 500mg | In Stock | 800 |
| 1g | In Stock | 1200 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3( 2H)-dione
SMILES Code:
OCCCC1=CC=C(C(N2C3=C(C)C=C(N(C)C(N4C)=O)C4=C3)=O)C5=C1C=CC=C5C2=O
InChi Code:
InChI=1S/C25H23N3O4/c1-14-12-20-21(27(3)25(32)26(20)2)13-19(14)28-23(30)178-4-7- 16-15(6-5-11-29)9-10-18(22(16)17)24(28)31/h4,7-10,12-13,29H,5-6,11H2,1- 3H3
InChi Key:
OFWWWKWUCDUISA-UHFFFAOYSA-N
Keyword:
BAV-299, BAV 299, BAY299, 2080306-23-4
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
BAY-299 potens et selectivus inhibitor bromodomain et PHD digitorum continentium (BRPF) dapibus familiae BRD1 (IC50 = 6 nM), etiam ut BRPF2 notus est, et secundus bromodomain transcriptionis initiationis factor TFIID subunits 1 (TAF1; IC50 = 13 nM).1 BAY-299 est >30 duplex selectivum supra BRPF1, BRPF3, BRD9 et ATAD2 et est >300-fold selective over BRD4.
Target: BRPF