Adavivint
Detail Produk
Tag produk
| Ukuran Paket | kasedhiyan | Rega (USD) |
| 100 mg | Ing Simpenan | 500 |
| 500 mg | Ing Simpenan | 800 |
| 1g | Ing Simpenan | 1200 |
| Ukuran liyane | Entuk Kutipan | Entuk Kutipan |
Jeneng Kimia:
N-(5-{3-[7-(3-fluorofenil)-1H-imidazo[4,5-c]piridin-2-yl]-1H-indazol-5-yl}piridin-3-yl)-3 - methylbutanamide
Kode SMILES:
CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1) = O
Kode Inchi:
InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34 -25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,( H,33,38)(H,34,35)(H,36,37)
Kunci InChi:
AQDWDWAYVBQMAM-UHFFFAOYSA-N
tembung kunci:
Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3
Kelarutan:Larut ing DMSO
Panyimpenan:0 - 4°C kanggo jangka cendhak (dina nganti minggu), utawa -20°C kanggo jangka panjang (sasi).
katrangan:
A novel cilik molekul Wnt pathway inhibitor karo EC50 saka 3 nM in vitro; ngindhuksi diferensiasi hMSC dadi kondrosit fungsional sing diwasa lan nyuda tingkat marker katabolik rawan; Ngartekno nambah Osteoarthritis Research Society International (OARSI) skor histologi lan biomarker ing model OA rodent.
Sasaran: WNT
