RGX-104 HCl

RGX-104 HCl
  • Aha:RGX-104 HCl
  • Nọmba katalọgụ:CPDB1632
  • Nọmba CAS:610318-03-1
  • Arọ Molecular:632.5452
  • Usoro kemịkalụ:C34H34Cl2F3NO3
  • Maka nyocha sayensị naanị, ọ bụghị maka ndị ọrịa.

    Nkọwa ngwaahịa

    Mkpado ngwaahịa

    Nha ngwugwu Nnweta Ọnụ ego (USD)
    100mg Dị na ngwaahịa 500
    500mg Dị na ngwaahịa 800
    1g Dị na ngwaahịa 1200
    Nha ndị ọzọ Nweta Quotes Nweta Quotes

    Aha kemịkalụ:

    (R) -2-[3-[3-[[2-Chloro-3- (trifluoromethyl) benzyl] (2,2-diphenylethyl) amino]-3-methylpropoxy] phenyl] acetic acid hydrochloride.

    Koodu Ọchịchọ:

    O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4 =CC=CC=C4)C)=C1.[H]Cl

    Koodu InChi:

    InChI=1S/C34H33ClF3NO3.ClH/c1-24(18-19-42-29-16-8-10-25(20-29)21-32(40)41)39(22-28-15-9- 17-31 (33 (28)35)34 (36,37)38)23-30 (26-11-4-2-5-12-26)27-13-6-3-7-14-27; /h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41);1H/t24-;/m1./s1

    Igodo InChi:

    LCMIYQOJZLRHTO-GJFSDDNBSA-N

    Okwu:

    RGX-104 HCl, RGX-104, RGX104, RGX 104, 610318-03-1

    Solubility:Soluble na DMSO

    Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

    Nkọwa:

    RGX-104 bụ onye na-anabata beta agonist nwere ike immunomodulating na antineoplastic. Mgbe nchịkwa ọnụ, RGX-104 na-ahọrọ ma jikọta na LXRbeta, si otú ahụ na-eme ka mgbasa ozi mgbasa ozi LXRbeta rụọ ọrụ, na-eduga na nsụgharị nke ụfọdụ mkpụrụ ndụ ihe na-egbochi tumor na mbelata nke ụfọdụ mkpụrụ ndụ ihe na-akwalite tumor. Nke a na-eme ka ngosipụta nke apolipoprotein E (ApoE), protein na-egbochi tumor, na mkpụrụ ndụ tumo na ụfọdụ mkpụrụ ndụ na-alụso ọrịa ọgụ. Nke a na-eme ka usoro ahụ ji alụso ọrịa ọgụ pụta, na-ebute mbelata nke immunosuppressive myeloid-derived suppressor cell (MDSCs), mkpụrụ ndụ tumo na mkpụrụ ndụ endothelial na microenvironment tumor. Nke a na-atụgharị mgbapụ ọgụ, na-eme ka nzaghachi mgbochi tumor na-egbochi mgbasa nke mkpụrụ ndụ tumo.

    Ebumnuche: LXRbeta


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