IT-901

Aha kemịkalụ:

5-[(2,4-Dimethoxy-1-naphthalenyl)methylene] dihydro-2-thioxo-4,6 (1H, 5H) -pyrimidinedione

Koodu Ọchịchọ:

O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S

Koodu InChi:

InChi=1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7 -12-15(20)18-17(24)19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)

Igodo InChi:

JHOPCCOYRKEHQU-UHFFFAOYSA-N

Okwu:

IT-901, IT901, IT 901, 1584121-99-2

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

Nkọwa:

"IT-901 bụ c-Rel Inhibitor nke na-emezi ihe Anticancer Properties na Hematologic Malignancies site na igbochi NF-κB-Controlled Oxidative Stress Responses. IT-901 na-egbochi NF-κB subunit c-Rel. IT-901 kwụsịrị ntinye aka-na-adabere na ya. ọrịa nnabata mgbe ị na-echekwa ọrụ graft-versus-lymphoma n'oge allogeneic Ntughari nyocha ọzọ nke IT-901 maka ọgwụgwọ nke lymphoma B-cell na-ekpughe ihe ndị antitumor na vitro na vivo na-enweghị mgbochi na NF-κB-based lymphoma IT-901 emeghị ka ọkwa dị elu nke ụdị oxygen na-arụ ọrụ leukocytes, nke na-akọwapụta akụrụngwa nke ọrịa kansa nke IT-901 bụ onye na-ahụ maka ọgwụgwọ ọhụụ na-agwọ ọrịa etuto lymphoid mmadụ graft-versus-ọrịa.

Ebumnuche: NF-kB