Ciforadenant

Non Chimik:

(S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)piridin-2-yl)methyl)-3H-[1,2 ,3] triazolo [4,5-d] pirimidin-5-amine

Kòd SMILES:

NC1=NC2=C(N=NN2CC3=NC(CO[C@H]4CCOC4)=CC=C3)C(C5=CC=C(O5)C)=N1

Kòd InChi:

InChI=1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13- 3-2-4-14(22-13)10-29-15-7-8-28-11-15/h2-6,15H,7-11H2,1H3,(H2,21,23,24)/ t15-/m0/s1

InChi kle:

KURQKNMKCGYWRJ-HNNXBMFYSA-N

Mot:

Ciforadenant, CPI-444, V81444, CPI444, CPI 444

Solibilite:Soluble nan DMSO

Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa)

Deskripsyon:

CPI-444 se yon antagonist ki pisan, ki disponib oralman, selektif nan reseptè adenosine A2A ki te byen tolere nan etid Ph 1/1b nan endikasyon ki pa nkoloji.

Sib: Adenosine A2A