Ozanimod

Inoa Kimia:

(S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2 -isopropoxybenzonitrile

SMILES Code:

N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

Code InChi:

InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3- 4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1- 2H3/t20-/m0/s1

Ki InChi:

XRVDGNKRPOAQTN-FQEVSTJZSA-N

huaʻōlelo:

Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).

wehewehe:

ʻO Ozanimod kahi modulator koho, loaʻa waha o ka sphingosine-1-phosphate (S1P) receptors S1P1 a me SIP5. Hoʻoulu ia i ka internalization o S1P1, hoʻemi i ka holo ʻana o B a me CCR7 (+) T lymphocytes, a hoʻemi i ka ʻāʻī a me nā ʻāpana maʻi i loko o nā ʻano maʻi autoimmune ʻekolu.

Pahuhopu: S1P