Adavivint
Huahana Huahana
Huahana Huahana
| Nui Puke | Loaʻa | Kumukuai (USD) |
| 100mg | Loaʻa | 500 |
| 500mg | Loaʻa | 800 |
| 1g | Loaʻa | 1200 |
| Nui hou aku | E kiʻi i nā huaʻōlelo | E kiʻi i nā huaʻōlelo |
Inoa Kimia:
N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 -methylbutanamide
SMILES Code:
CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1)=O
Code InChi:
InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34 -25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,( H,33,38)(H,34,35)(H,36,37)
Ki InChi:
AQDWDWAYVBQMAM-UHFFFAOYSA-N
huaʻōlelo:
Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3
Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO
Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).
wehewehe:
ʻO kahi mole liʻiliʻi liʻiliʻi Wnt ala hoʻopololei me EC50 o 3 nM in vitro; hoʻoulu i ka hoʻokaʻawale ʻana o ka hMSC i loko o nā chondrocytes makua, hana a hoʻemi i nā pae cartilage catabolic marker; hoʻomaikaʻi maikaʻi i ka Osteoarthritis Research Society International (OARSI) nā helu mōʻaukala a me nā biomarkers i loko o kahi kumu hoʻohālike OA rodent.
Pahuhopu: WNT
