Adavivint
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 100mg | A Stock | 500 |
| 500mg | A Stock | 800 |
| 1g | A Stock | 1200 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 - methylbutanamide
Lambar SMILES:
CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1) = O
Lambar InChi:
InChi=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9- 16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)
InChi Key:
AQDWDWAYVBQMAM-UHFFFAOYSA-N
Mabuɗin kalma:
Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).
Bayani:
Wani sabon ƙaramin ƙwayar ƙwayar cuta Wnt mai hana hanya tare da EC50 na 3 nM a cikin vitro; yana haifar da bambancin hMSC a cikin balagagge, chondrocytes masu aiki kuma yana rage matakan alamar catabolic guringuntsi; yana inganta ƙididdiga na tarihin Osteoarthritis Research Society International (OARSI) da ƙididdiga na biomarkers a cikin ƙirar OA rodent.
manufa: WNT
