TNG-908; EX-A7872

Ainm Ceimigeach:

N-(6-amino-5-methylpyridin-3-il)-2-((2R,5S)-2-(benzo[d]thiazol-5-yl)-5-methylpiperidin-1-yl)-2- oxoacetamide

Còd SMILES:

CC1=CC(NC(C(N2[C@H)(C3=CC=C(SC=N4)C4=C3)CC[C@@H](C2)C)=O)=O)=CN =C1N

Còd InChi:

InChI=1S/C21H23N5O2S/c1-12-3-5-17(14-4-6-18-16(8-14)24-11-29-18)26(10-12)21(28)20( 27) 25-1 5-7-13(2)19(22)23-9-15/h4,6-9,11-12,17H,3,5,10H2,1-2H3,(H2,22,23)(H, 25,27)/t12-,17+/m0/s1

iuchair InChi:

NXXBDYHMHHINFC-YVEFUNNKSA-N

Facal-luirg:

2760481-53-4 CAS: 2760481-53-4 ； CAS: 2760481-53-4 ；TNG908；TNG-908；TNG 908；EX-A7872

Solubility: 

Stòradh:Tioram, dorcha agus aig 0 -4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).

Tuairisgeul:

Tha TNG908 na neach-dìon PRMT5 synergistic MTAP.

Targaid: PRMT5