AZD4547
Mion-fhiosrachadh toraidh
Bathar Tags
| Meud pacaid | Ri fhaotainn | Prìs (USD) |
| 1g | Anns a’ bhùth | 750 |
| 5g | Anns a’ bhùth | 3000 |
| Barrachd mheudan | Faigh Quotes | Faigh Quotes |
Ainm Ceimigeach:
N-(5- (3,5-dimethoxyphenethyl)-1H-pyrazol-3-il)-4-((3S,5R)-3,5-dimethylpiperazin-1-il)benzamide
Còd SMILES:
O=C(NC1=NNC(CCC2=CC(OC)=CC(OC)=C2)=C1)C3=CC=C(N4C[C@H)(C)N[C@H](C)C4 )C=C3
Còd InChi:
InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21( 29-30-25)8-5 -19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,( H2,28,29,30,32)/t17-,18+
iuchair InChi:
VRQMAABPASPXMW-HDICACEKSA-N
Facal-luirg:
AZD4547, AZD-4547, AZD 4547, 1035270-39-3
Solubility:Soluble ann an DMSO
Stòradh:0 - 4 ° C airson geàrr-ùine (làithean gu seachdainean), no -20 ° C airson ùine fhada (mìosan)
Tuairisgeul:
Tha AZD 4547 na neach-dìon roghnach den tyrosine kinase receptor factar fàis fibroblast (FGFR) le luachan IC50 de 0.2, 2.5, agus 1.8 nM airson FGFR1, 2, agus 3, fa leth.
Targaid: FGFR
