| KASS nr | Toote nimi | Kirjeldus |
| CPD100391 | SHP394 | |
| CPD100390 | SHP389 (vaba alus) | |
| CPD3242 | RMC-4550 | RMC-4550 on tugev ja selektiivne SHP2 inhibiitor. RMC-4550 tuvastati kõrgekvaliteedilise tööriistaühendina SHP2 rolli uurimiseks kasvajabioloogias nii in vitro kui ka in vivo närilistel. SHP2 on konvergentne signaalisõlm ja SHP2 inhibeerimine on efektiivne nii ülesvoolu (RTK-juhitud) kui ka allavoolu (RAS-GTP-st sõltuvate) mutatsioonide sihtimisel RAS-MAPK rajas. |
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