Vardenafil

Orukọ Kemikali:

2- (2-ethoxy-5- ((4-ethylpiperazin-1-yl) sulfonyl) phenyl) -5-methyl-7-propyl-3,5,6,7-tetrahydro-4H-5l4-imidazo[1, 5-a [1,3,5]triazin-4-ọkan

KỌỌDỌ SMILES:

O=C(NC(C1=CC(S(=O))(N2CCN(CC)CC2)=O)=CC=C1OCC=N3)[N]4(C)C3=CN(CCC)C4

Koodu InChi:

InChi=1S/C23H35N6O4S/c1-5-10-27-16-21-24-22(25-23(30)29(21,4)17-27)19-15-18(8-9-20(8-9-20) 19) 33-7-3)34 (31,32)28-13-11-26 (6-2)12-14-28/h8-9,15-16H,5-7,10-14,17H2,1- 4H3, (H,24,25,30)

Bọtini InChi:

UWRWYSQUBZFWPU-UHFFFAOYSA-N

Koko-ọrọ:

Vardenafil, Levitra, Staxyn, Vivanza, BAY 38-9456, BAY-38-9456, BAY38-9456, 224785-90-4

Solubility:Tiotuka ni DMSO

Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu)

Apejuwe:

Vardenafil, ti a tun mọ ni BAY 38-9456, jẹ inhibitor PDE5 ti a lo fun atọju aiṣedeede erectile. Awọn itọkasi Vardenafil ati awọn ilodisi-itọkasi jẹ kanna pẹlu awọn inhibitors PDE5 miiran; o ni ibatan pẹkipẹki ni iṣẹ si sildenafil citrate (Viagra) ati tadalafil (Cialis). Iyatọ laarin moleku vardenafil ati sildenafil citrate jẹ ipo atom nitrogen ati iyipada ti ẹgbẹ piperazine piperazine ti sildenafil si ẹgbẹ ethyl. Tadalafil jẹ iyatọ ti o yatọ si mejeji sildenafil ati vardenafil. Vardenafil jo kukuru akoko imunadoko jẹ afiwera si ṣugbọn diẹ gun ju ti sildenafil lọ.

afojusun: PDE5