PCO371

PCO371
  • Orukọ:PCO371
  • Katalogi No.CPD2050
  • CAS No.:1613373-33-3
  • Ìwọ̀n Molikula:635.20
  • Fọọmu Kemikali:C29H32F3N5O6S
  • Fun iwadi ijinle sayensi nikan, kii ṣe fun awọn alaisan.

    Alaye ọja

    ọja Tags

    Iwọn Pack Wiwa Iye owo (USD)

    Orukọ Kemikali:

    1- (3,5-dimethyl-4- (2-(4-oxo-2------------) phenyl-1,3,8-triazaspiro [4.5] dec-1-en-8-yl sulfonyl) ethyl) phenyl) -5,5-dimethylimidazolidine-2,4-dione.

    KỌỌDỌ SMILES:

    O=C1NC(C(C)(C)N1C2=CC(C)=C(CCS(=O)(N(CC3)CCC3(N=C(C4=CC)=C(OC(F)(F)F) )C=C4)N5)C5=O)=O)C(C)=C2)=O

    Koodu InChi:

    InChi=1S/C29H32F3N5O6S/c1-17-15-20(37-26(40)34-24(38)27(37,3)4)16-18(2)22(17)9-14-44( 41,42)36-12-10-28 (11 -13-36)25 (39)33-23 (35-28)19-5-7-21 (8-6-19)43-29(30,31)32/h5-8,15-16H,9 -14H2,1-4H3,(H,33,35,39)(H,34,38,40)

    Bọtini InChi:

    LDZJFVOUPUFOHX-UHFFFAOYSA-N

    Koko-ọrọ:

    PCO371; PCO-371; PCO 371

    Solubility: 

    Ibi ipamọ: 

    Apejuwe:

    PCO371 jẹ agonist PTHR1 ti o lagbara ati yiyan fun itọju hypoparathyroidism. Isakoso ẹnu ti PCO371 si awọn eku osteopenic nfa ilosoke pataki ninu iyipada eegun pẹlu ilosoke opin ni ibi-egungun. Ninu awọn eku hypocalcemic, PCO371 ṣe atunṣe awọn ipele kalisiomu omi ara laisi jijẹ kalisiomu ito, ati pẹlu awọn ipa ti o lagbara ati gigun ju awọn abẹrẹ PTH lọ.

    afojusun: PTHR1


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