SJ-01

Orukọ Kemikali:

(E) -1- (3- (3,4,5-trimethoxyphenyl)acryloyl) -5,6-dihydropyridin-2 (1H) -ọkan

KỌỌDỌ SMILES:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

Koodu InChi:

InChi=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

Bọtini InChi:

VABYUUZNAVQNPG-BQYQJAHWSA-N

Koko:

20069-09-4;CAS:20069-09-4;CAS:20069-09-4;Piperlongumine; Piplatine.

Solubility:Tiotuka ni DMSO

Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

Apejuwe:

Piperlongumine, ti a tun mọ ni Piplartine, jẹ alkaloid / amide ti nṣiṣe lọwọ biologically lati ata, bi lati ata gigun (Piper longum L. - Piperaceae). Ata gigun jẹ ọkan ninu lilo pupọ julọ ni oogun Ayurvedic, eyiti a lo lati tọju ọpọlọpọ awọn arun, pẹlu awọn èèmọ. Awọn iṣẹ elegbogi ti a royin ti piplartine pẹlu cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, and s. Lara awọn ipa elegbogi pupọ ti piplartine, ohun-ini anticancer jẹ eyiti o ni ileri julọ.

Ibi-afẹde: Piperlongumine jẹ alkaloid ti o ṣe idiwọ iyipada ti myofibroblasts nipa didi ipa ọna ifihan erk1/2