NST-628

Orukọ Kemikali:

3-[[3-fluoro-2- (methylsulfamoylamino) pyridin-4-yl]methyl]-7- (3-fluoropyridin-2-yl) oxy-4-methylchromen-2-ọkan

KỌỌDỌ SMILES:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

Koodu InChi:

InChi=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26) ,28)

Bọtini InChi:

YQSZJOABXRROQR-UHFFFAOYSA-N

Koko-ọrọ:

3002056-30-3;CAS:3002056-30-3;CAS:3002056-30-3;NST-628;NST628;NST 628

Solubility: 

Ibi ipamọ:Gbẹ, dudu ati ni 0 -4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (awọn oṣu si ọdun).

Apejuwe:

NST-628 jẹ jeli molikula ipa ọna MAPK pẹlu agbara idena ọpọlọ-ẹjẹ, eyiti o le ṣe idiwọ phosphorylation RAF ati imuṣiṣẹ MEK.

Ifojusi: RAF phosphorylation ati MEK