Mirogabalin besylate

Orukọ Kemikali:

((1R,5S,6S) -6- (carboxymethyl) -3-ethylbicyclo [3.2.0] hept-3-en-6-yl) methanaminium benzenesulfonate

KỌỌDỌ SMILES:

CCC(C1)=C[C@]2([H])[C@@]1([H])C[C@]2(CN)CC(O)=OO=S(C3=CC=CC) =C3)(O)=O

Koodu InChi:

InChi=1S/C12H19NO2.C6H6O3S/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8;7-10(8,9) 6-4 -2-1-3-5-6/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15);1-5H,(H,7,8,9) /t9-,10-,12-;/m1./s1

Bọtini InChi:

OKJXJRVWXYRSAN-TXULWXBWSA-N

Koko-ọrọ:

Mirogabalin, Mirogabalin besylate, 1138245-21-2,1138245-13-2,DS-5565, DS5565, DS 5565

Solubility:DMSO; H2O

Ibi ipamọ: 

Apejuwe:

Mirogabalin, ti a tun mọ ni DS-5565, jẹ ligand α2δ-1 ti o ni idagbasoke fun irora ti o ni nkan ṣe pẹlu neuropathy agbeegbe dayabetik, fibromyalgia, ati neuralgia postherpetic. O ti ṣe afihan awọn abajade ileri ni Awọn idanwo ile-iwosan Ipele II fun itọju ti irora neuropathic agbeegbe dayabetik.

Àfojúsùn: α2δ-1