I-BAY-293

I-BAY-293
  • Igama:I-BAY-293
  • Inombolo yekhathalogu:CPD2807
  • Inombolo yeCAS:2244904-70-7
  • Ubunzima beMolekyuli:448.585
  • Ifomula yemichiza:I-C25H28N4O2S
  • Kuphando lwenzululwazi kuphela, hayi izigulane.

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    Iithegi zeMveliso

    Ubungakanani bePakethi Ubukho Ixabiso (USD)

    Igama leMchiza:

    (R)-6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine

    Ikhowudi yoncumo:

    C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3

    Ikhowudi ye-InChi:

    InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22( 30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29 )/t15-/m1/s1

    Isitshixo se-InChi:

    WEGLOYDTDILXDA-OAHLLOKOSA-N

    Igama elingundoqo:

    I-BAY-293,BAY 293,BAY293

    Ukunyibilika: 

    Ugcino: 

    Inkcazo:

    I-BAY-293 yi-SOS1 inhibitor enamandla evimba ukusebenza kwe-RAS ngokuphazamiseka kwe-RAS-SOS1 ukusebenzisana. I-BAY-293) inqanda ukusebenzisana kwe-KRAS-SOS1 kunye ne-IC50 ye-21 nM kwaye luphando lweekhemikhali oluxabisekileyo kuphando lwexesha elizayo.

    Ithagethi: SOS1 inhibitor


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