I-BAY-293
Iinkcukacha zeMveliso
Iithegi zeMveliso
Ubungakanani bePakethi | Ubukho | Ixabiso (USD) |
Igama leMchiza:
(R)-6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine
Ikhowudi yoncumo:
C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3
Ikhowudi ye-InChi:
InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22( 30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29 )/t15-/m1/s1
Isitshixo se-InChi:
WEGLOYDTDILXDA-OAHLLOKOSA-N
Igama elingundoqo:
I-BAY-293,BAY 293,BAY293
Ukunyibilika:
Ugcino:
Inkcazo:
I-BAY-293 yi-SOS1 inhibitor enamandla evimba ukusebenza kwe-RAS ngokuphazamiseka kwe-RAS-SOS1 ukusebenzisana. I-BAY-293) inqanda ukusebenzisana kwe-KRAS-SOS1 kunye ne-IC50 ye-21 nM kwaye luphando lweekhemikhali oluxabisekileyo kuphando lwexesha elizayo.
Ithagethi: SOS1 inhibitor