ARS-1630
Kuphando lwenzululwazi kuphela, hayi izigulane.
Iinkcukacha zeMveliso
Iithegi zeMveliso
| Ubungakanani bePakethi | Ubukho | Ixabiso (USD) |
| 100mg | Ikhona evenkileni | 800 |
| 500mg | Ikhona evenkileni | 1500 |
| 1g | Ikhona evenkileni | 2000 |
| Iisayizi ezininzi | Fumana iiQuotes | Fumana iiQuotes |
Igama leMchiza:
(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
Ikhowudi yoncumo:
"C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1 )=O.[R]
Ikhowudi ye-InChi:
Isitshixo se-InChi:
Igama elingundoqo:
ARS1630, ARS 1630, ARS-1630, 1698055-86-5
Ukunyibilika:Inyibilika kwi-DMSO
Ugcino:0 - 4°C ixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20°C ixesha elide (iinyanga)
Inkcazo:
I-ARS-1630 yi-atropisomer ye-R-conformational ye-ARS-1620, i-1,000-fold less potent than ARS-1620 (1.2 ± 0.6 M-1s-1) kwaye ngaloo ndlela isebenza njengento eyodwa yokulawula engasebenziyo.
Ekujoliswe kuko: KRAS (K-Ras G12C)
