IT-901

IT-901
  • Igama:IT-901
  • Inombolo yekhathalogu:CPDB1661
  • Inombolo yeCAS:1584121-99-2
  • Ubunzima beMolekyuli:342.369
  • Ifomula yemichiza:I-C17H14N2O4S
  • Kuphando lwenzululwazi kuphela, hayi izigulane.

    Iinkcukacha zeMveliso

    Iithegi zeMveliso

    Ubungakanani bePakethi Ubukho Ixabiso (USD)
    100mg Ikhona evenkileni 500
    500mg Ikhona evenkileni 800
    1g Ikhona evenkileni 1200
    Iisayizi ezininzi Fumana iiQuotes Fumana iiQuotes

    Igama leMchiza:

    5 - [(2,4-Dimethoxy-1-naphthalenyl) methylene]dihydro-2-thioxo-4,6 (1H,5H) -pyrimidinedione

    Ikhowudi yoncumo:

    O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S

    Ikhowudi ye-InChi:

    InChI=1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7-12-15(20)18-17( 24)19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)

    Isitshixo se-InChi:

    JHOPCCOYRKEHQU-UHFFFAOYSA-N

    Igama elingundoqo:

    IT-901, IT901, IT 901, 1584121-99-2

    Ukunyibilika:Inyibilika kwi-DMSO

    Ugcino:0 - 4°C ixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20°C ixesha elide (iinyanga).

    Inkcazo:

    "I-IT-901 yi-c-Rel Inhibitor Edibanisa iiPropati ze-Anticancer kwi-Hematologic Malignancies ngokuVimba i-NF-κB-Controlled Oxidative Stress Responses. I-IT-901 ivimbela ngokukhawuleza i-NF-κB subunit c-Rel. IT-901 igxininiswe i-graft-versus- isifo somkhosi ngelixa ugcina umsebenzi we-graft-versus-lymphoma ngexesha lokutshintshwa kwe-allogeneic Uvavanyo oluqhubekayo lwe-IT-901 kunyango lwe-B-cell lymphoma luveze iipropati ze-antitumor kwi-vitro kunye ne-vivo ngaphandle kwesithintelo kwi-NF-κB-exhomekeke kwi-lymphoma. I-901 ayizange inyuse amanqanaba e-oksijini esebenzayo kwi-leukocyte eqhelekileyo, ebonisa iimpawu zayo ezikhethiweyo zomhlaza we-IT-901 yi-agent yonyango ye-novel yokunyanga i-lymphoid tumors kunye nesifo esixutywe ne-host.

    Ithagethi: NF-kB


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