TNG462
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Pangalan ng Kemikal:
N-(6-amino-5-ethylpyridin-3-yl)-2-(5-methyl-2-(2-(1-methylpiperidin-4-yl)benzo[d]thiazol-5-yl)piperidin-1 -yl)-2-oxoacetamide
SMILES Code:
O=C(NC1=CC(CC)=C(N)N=C1)C(N1[C@@H](C2=CC=C3C(N=C(S3)C3CCN(C)CC3)=C2) CC[C@H](C)C1)=O
InChi Code:
InChI=1S/C28H36N6O2S/c1-4-18-13-21(15-30-25(18)29)31-26(35)28(36)34-16-17(2)5-7-23( 34)20-6-8-24-22(14-20)32- 27(37-24)19-9-11-33(3)12-10-19/h6,8,13-15,17,19,23H,4-5,7,9-12,16H2,1- 3H3,(H2,29,30)(H,31,35)/t17-,23+/m0/s1
InChi Key:
DHAGMIPSRSPWSH-GAJHUEQPSA-N
Keyword:
2760483-96-1;CAS:2760483-96-1;CAS:2760483-96-1;TNG462;TNG 462;TNG-462
Solubility:
Imbakan:Tuyo, madilim at nasa 0 -4 C para sa panandaliang panahon (araw hanggang linggo) o -20 C para sa pangmatagalan (buwan hanggang taon).
Paglalarawan:
Ang TNG-462 ay isang mabisang pasalitang selective PRMT5 inhibitor.
Target: PRMT5