NST-628
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Pangalan ng Kemikal:
3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one
SMILES Code:
FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1
InChi Code:
InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29 )16(12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,( H,26,28)
InChi Key:
YQSZJOABXRROQR-UHFFFAOYSA-N
Keyword:
3002056-30-3;CAS:3002056-30-3;CAS:3002056-30-3;NST-628;NST628;NST 628
Solubility:
Imbakan:Tuyo, madilim at nasa 0 -4 C para sa panandaliang panahon (araw hanggang linggo) o -20 C para sa pangmatagalan (buwan hanggang taon).
Paglalarawan:
Ang NST-628 ay isang MAPK pathway molecular gel na may blood-brain barrier permeability, na maaaring makapigil sa RAF phosphorylation at MEK activation.
Target: RAF phosphorylation at MEK