GDC6036; GDC6036 atropisomer

GDC6036; GDC6036 atropisomer
  • Pangalan:2-Propen-1-one, 1-[(3S)-4-[7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-
  • Catalog No.:CPD111670
  • CAS No.:2417917-17-8
  • Molekular na Bigat:622.06
  • Formula ng Kemikal:C29 H32 Cl F4 N7 O2
  • Para sa siyentipikong pananaliksik lamang, hindi para sa mga pasyente.

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    Pangalan ng Kemikal:

    2-Propen-1-one, 1-[(3S)-4-[7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-

    SMILES Code:

    C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F )C3=NC(OC[C@H]5N(C)CCC5)=N2)CC1)=O

    InChi Code:

    InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32, 33)34)15(2)11-20(35)36-2 6)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6- 10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1

    InChi Key:

    ZRBPIAWWRPFDPY-IRXDYDNUSA-N

    Keyword:

    2417917-17-8;CAS:2417917-17-8;CAS:2417917-17-8;GDC6036 atropisomer; GDC-6036; GDC 6036; GDC6036

    Solubility: 

    Imbakan:Tuyo, madilim at nasa 0 - 4 C para sa maikling panahon (araw hanggang linggo) o -20 C para sa pangmatagalan (buwan hanggang taon).

    Paglalarawan:

    Ang GDC6036 anti rotation isomer ay naglalaman ng dalawang uri ng GDC6036 anti rotation isomer. GDC-6036, Kilala rin bilang RG6330, ito ay isang pasalitang bioavailable, napakahusay, at pumipili ng KRAS G12C inhibitor.

    Target: KRAS G12C




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