Mpinzani wa kuumwa-3
Maelezo ya Bidhaa
Lebo za Bidhaa
Ukubwa wa Pakiti | Upatikanaji | Bei (USD) |
Jina la Kemikali:
(E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazol-1-yl)lakini-2- en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-hydroxypropoxy)-1H-benzo[d]imidazole-5-carboxamido
Msimbo wa SMILES:
O=C(N)C1=CC=C(N(C(NC(C2=CC(C)=NN2CC)=O)=N3)C/C=C/CN4C5=C(N=C4NC(C6=CC) (C)=NN6CC)=O)C=C(C(N)=O)C=C5OCCO)C3=C1
Msimbo wa InChi:
InChI=1S/C37H42N12O6/c1-5-48-28(16-21(3)44-48)34(53)42-36-40-25-18-23(32(38)51)10-11- 27(25)46(36)12-7-8-13-47-31-26(19-24(33(39)52)20-30(31)55-15-9-14-50)41- 37(47)43-35(54)29-17-22(4)45-49(29)6-2/h7-8,10-11,16-20,50H,5-6,9,12- 15H2,1-4H3,(H2,38,51)(H2,39,52)(H,40,42,53)(H,41,43,54)/b8-7+
Ufunguo wa InChi:
VHCDRDBBENBVEK-BQYQJAHWSA-N
Neno muhimu:
Umumunyifu:
Hifadhi:
Maelezo:
STING agonist-3, iliyotolewa kutoka hataza WO2017175147A1 (mfano 10), ni agonisti ya kuchagua na isiyo ya nyukleotidi ya molekuli ndogo ya STING yenye pEC50 na pIC50 ya 7.5 na 9.5, mtawalia. STING agonist-3 ina athari ya kudumu ya kupambana na tumor na uwezo mkubwa wa kuboresha matibabu ya saratani
Lengo: STING