Ifebemtinib,BI 853520

Ifebemtinib,BI 853520
  • Jina:4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl)oksi]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro- 5-methoxy-N-(1-methyl-4-piperidinyl) benzamide
  • Nambari ya Katalogi:CPD111050
  • Nambari ya CAS:1227948-82-4
  • Uzito wa Masi:588.55
  • Mfumo wa Kemikali:C28 H28 F4 N6 O4
  • Kwa utafiti wa kisayansi tu, sio kwa wagonjwa.

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    Jina la Kemikali:

    4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl)oksi]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro- 5-methoxy-N-(1-methyl-4-piperidinyl) benzamide

    Msimbo wa SMILES:

    O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

    Msimbo wa InChi:

    InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,3 1)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/h4-6,11-13,16H,7- 10,14H2,1-3H3,(H,34,39)(H,33,35,36)

    Ufunguo wa InChi:

    ULMMVBPTWVRPSI-UHFFFAOYSA-N

    Neno muhimu:

    1227948-82-4;CAS:1227948-82-4;CAS:1227948-82-4;Ifebemtinib;BI 853520

    Umumunyifu:Mumunyifu katika DMSO, si katika maji

    Hifadhi:0 - 4 C kwa muda mfupi (siku hadi wiki), au -20 C kwa muda mrefu (miezi).

    Maelezo:

    Ifebemtinib (BI 853520) ni kizuizi chenye nguvu cha kinase ya kushikamana ya focal (FAK) yenye shughuli ya mdomo.

    Lengo: Kizuizi chenye Nguvu cha FAK




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