Divarasib,GDC 6036

Jina:1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one

Nambari ya Katalogi:CPD112857

Nambari ya CAS:2417987-45-0

Uzito wa Masi:622.06

Mfumo wa Kemikali:C29 H32 Cl F4 N7 O2

Kwa utafiti wa kisayansi tu, sio kwa wagonjwa.

Tutumie barua pepe Pakua kama PDF

Maelezo ya Bidhaa

Lebo za Bidhaa

Ukubwa wa Pakiti	Upatikanaji	Bei (USD)
0.1G	Katika Hisa	550
0.5G	Katika Hisa	860
1G	Katika Hisa	1250

Jina la Kemikali:

1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one

Msimbo wa SMILES:

NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F

Msimbo wa InChi:

InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,) 33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17) 4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)

Ufunguo wa InChi:

ZRBPIAWWRPFDPY-UHFFFAOYSA-N

Neno muhimu:

2417987-45-0;CAS:2417987-45-0;CAS:2417987-45-0;Divarasib;GDC 6036

Umumunyifu:UmumunyifuIli kuamuliwa

Hifadhi:Kavu, giza na kwa 0 - 4 C kwa muda mfupi (siku hadi wiki) au -20 C kwa muda mrefu (miezi hadi miaka).

Maelezo:

Divarasib (GDC-6036) ni kizuizi cha KRAS G12C chenye uwezo wa kumeza wa bioavailability na uteuzi.

Lengo: KRAS G12C inhibitor

Iliyotangulia: Asundexian,BI1265162

Inayofuata: 4,6-dichloro-5-fluoro-2-(methylsulfanyl)pyrimidine