AMG-510
Maelezo ya Bidhaa
Lebo za Bidhaa
| Ukubwa wa Pakiti | Upatikanaji | Bei (USD) |
| 1g | katika hisa | 1300 |
| 5g | katika hisa | 6000 |
| 10g | katika hisa | 10500 |
Jina la Kemikali:
4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl) )pyrido[2,3-d]pyrimidin-2(1H)-moja
Msimbo wa SMILES:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
Msimbo wa InChi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6- 11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
Ufunguo wa InChi:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Neno muhimu:
AMG-510; AMG 510; AMG510
Umumunyifu:
Hifadhi:
Maelezo:
AMG-510 ni kizuizi chenye nguvu cha KRAS G12C. AMG-510 inalenga kwa kuchagua kibadilishaji cha KRAS p.G12C, katika kiwango cha DNA, RNA au protini, na inazuia, kwa njia ambayo bado haijafafanuliwa, usemi wa na/au uashiriaji wa seli za uvimbe kupitia kibadilishaji cha KRAS p.G12C. Hii inaweza kuzuia ukuaji wa seli za uvimbe zinazoonyesha KRAS p.G12C
Lengo: KRAS
