BN104

Jina:(2-(6-(2-(4-cyclopropylpyrimidin-5-yl)-4-fluorophenoxy)-1,2,4-triazin-5-yl)-2,7-diazaspiro[3.5]nonan-7-yl )(1S,3aR,6aS)-octahydrocyclopenta[c]pyrrol-1-yl)methanoni

Nambari ya Katalogi:CPDP801669

Nambari ya CAS:2938995-50-5

Uzito wa Masi:570.66

Mfumo wa Kemikali:C31 H35 F N8 O2

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Jina la Kemikali:

(2-(6-(2-(4-cyclopropylpyrimidin-5-yl)-4-fluorophenoxy)-1,2,4-triazin-5-yl)-2,7-diazaspiro[3.5]nonan-7-yl )(1S,3aR,6aS)-octahydrocyclopenta[c]pyrrol-1-yl)methanoni

Msimbo wa SMILES:

[H][C@@]12CCC[C@]1([H])[C@H](NC2)C(=O)N3CCC4(CN(C4)C5=C(OC6=CC=C(F) C=C6C7=CN=CN=C7C8CC8)N=NC=N5)CC3

Msimbo wa InChi:

1S/C31H35FN8O2/c32-21-6-7-25(23(12-21)24-14-33-17-35-26(24)19-4-5-19)42-29-28(36- 18-37-38-29)40-15-31(16-40)8-1 0-39(11-9-31)30(41)27-22-3-1-2-20(22)13-34-27/h6-7,12,14,17-20,22,27, 34H,1-5,8-11,13,15-16H2/t20-,22-,27-/m0/s1

Ufunguo wa InChi:

XDXAYPYOHXUEAM-CLHVYKLBSA-N

Neno muhimu:

2938995-50-5;CAS:2938995-50-5;CAS:2938995-50-5;BN-104;BN104;BN 104

Umumunyifu:

Hifadhi:Kavu, giza na kwa 0 -4 C kwa muda mfupi (siku hadi wiki) au -20 C kwa muda mrefu (miezi hadi miaka)

Maelezo:

BN-104 (BNM-1192) inaweza kuzuia mwingiliano wa Menin MLL na inaweza kutumika katika utafiti wa saratani, kama vile leukemia ya papo hapo ya myeloid.

Lengo: Menin-MLL

Iliyotangulia: Cyclopenta[c]pyrrole-1,2(1H)-dicarboxylic acid, hexahydro-, 2-(1,1-dimethylethyl) 1-ethyl ester, (1S,3aR,6aS)

Inayofuata: ethyl 2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol- 1-yl)acetate