BI-3812

Jina la Kemikali:

1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin -2-yl)-N,N-dimethylpiperidine-4-carboxamide

Msimbo wa SMILES:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C(C(OCC(NC)=O)=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

Msimbo wa InChi:

InChI=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18(27)13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6- 9,14H2,1-5H3,(H,28,35)(H,29,30,31)

Ufunguo wa InChi:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Neno muhimu:

BI-3812; BI 3812; BI3812

Umumunyifu: 

Hifadhi: 

Maelezo:

BI-3812 ni kizuizi chenye nguvu cha mwingiliano wa kikoa cha BTB/POZ cha BCL6 na vikandamizaji kadhaa. Hufanya kazi kwa kuzuia uundaji changamano wa BCL6::Co-repressor.

Lengo: BCL6