EAI-045
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
Magaca Kiimikada:
2- (5-fluoro-2-hydroxyphenyl) -2- (3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl) acetamide
Koodhka dhoola cadeynta:
O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O
Koodhka InChi:
InChi=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11- 3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
Furaha InChi:
YTUFHOKUFOQRDF-UHFFFAOYSA-N
Ereyga muhiimka ah:
EAI-045, EAI045, EAI 045, 1942114-09-1
Xalka:Ku milmay DMSO
Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo)
Sharaxaad:
EAI045 waa mid awood leh oo doorta EGFR horjooge. EAI045 waxay beegsataa doorsoon mutants EGFR u adkeysi u leh dawada laakiin waxay u tudhaysaa soo dhawaynta nooca duurjoogta ah. EAI045 waxay joojisaa L858R/T790M-mutant EGFR oo leh awood hoose oo nanomolar ah oo ku jirta qiimaynta biochemical.
Hadafka: EGFR