EAI-045

EAI-045
  • Magaca:EAI-045
  • Lambarka buugga:CPDB0934
  • Lambarka CAS:1942114-09-1
  • Miisaanka Molecular:383.4
  • Foomka Kiimikada:C19H14FN3O3S
  • Cilmi baaris cilmiyeed oo keliya, ma ahan bukaanka.

    Faahfaahinta Alaabta

    Tags Product

    Cabbirka Xidhmada Helitaanka Qiimaha (USD)

    Magaca Kiimikada:

    2- (5-fluoro-2-hydroxyphenyl) -2- (3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl) acetamide

    Koodhka dhoola cadeynta:

    O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O

    Koodhka InChi:

    InChi=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11- 3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)

    Furaha InChi:

    YTUFHOKUFOQRDF-UHFFFAOYSA-N

    Ereyga muhiimka ah:

    EAI-045, EAI045, EAI 045, 1942114-09-1

    Xalka:Ku milmay DMSO

    Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo)

    Sharaxaad:

    EAI045 waa mid awood leh oo doorta EGFR horjooge. EAI045 waxay beegsataa doorsoon mutants EGFR u adkeysi u leh dawada laakiin waxay u tudhaysaa soo dhawaynta nooca duurjoogta ah. EAI045 waxay joojisaa L858R/T790M-mutant EGFR oo leh awood hoose oo nanomolar ah oo ku jirta qiimaynta biochemical.

    Hadafka: EGFR


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