Adavivint

Adavivint
  • Magaca:Adavivint; SM04690
  • Lambarka buugga:CPDD1633
  • Lambarka CAS:1467093-03-3
  • Miisaanka Molecular:505.55
  • Foomka Kiimikada:C29H24FN7O
  • Cilmi baaris cilmiyeed oo keliya, ma ahan bukaanka.

    Faahfaahinta Alaabta

    Tags Product

    Cabbirka Xidhmada Helitaanka Qiimaha (USD)
    100mg In Stock 500
    500mg In Stock 800
    1g In Stock 1200
    Cabiro badan Hel Xigasho Hel Xigasho

    Magaca Kiimikada:

    N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 -methylbutanamide

    Koodhka dhoola cadeynta:

    CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1)=O

    Koodhka InChi:

    InChi=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34 -25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,( H,33,38)(H,34,35)(H,36,37)

    Furaha InChi:

    AQDWDWAYVBQMAM-UHFFFAOYSA-N

    Ereyga muhiimka ah:

    Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3

    Xalka:Ku milmay DMSO

    Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).

    Sharaxaad:

    Moleekule yar oo cusub Wnt pathway inhibitor oo leh EC50 of 3 nM in vitro; waxay keentaa kala soocida hMSC ee qaangaadhka ah, chondrocytes ee shaqaynaysa waxayna hoos u dhigtaa heerarka calamadaha carjawda; si weyn ayuu u wanaajiyaa Osteoarthritis Research Society International (OARSI) buundooyinka histology iyo biomarkers ee qaabka OA jiirka.

    Ujeedka: WNT


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