Adavivint
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
100mg | In Stock | 500 |
500mg | In Stock | 800 |
1g | In Stock | 1200 |
Cabiro badan | Hel Xigasho | Hel Xigasho |
Magaca Kiimikada:
N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 -methylbutanamide
Koodhka dhoola cadeynta:
CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1)=O
Koodhka InChi:
InChi=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34 -25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,( H,33,38)(H,34,35)(H,36,37)
Furaha InChi:
AQDWDWAYVBQMAM-UHFFFAOYSA-N
Ereyga muhiimka ah:
Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3
Xalka:Ku milmay DMSO
Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).
Sharaxaad:
Moleekule yar oo cusub Wnt pathway inhibitor oo leh EC50 of 3 nM in vitro; waxay keentaa kala soocida hMSC ee qaangaadhka ah, chondrocytes ee shaqaynaysa waxayna hoos u dhigtaa heerarka calamadaha carjawda; si weyn ayuu u wanaajiyaa Osteoarthritis Research Society International (OARSI) buundooyinka histology iyo biomarkers ee qaabka OA jiirka.
Ujeedka: WNT