BAY-850
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
N-((R)-1-(((1s,4S)-4-aminocyclohexyl)amino)-3-(4-cyanophenyl)propan-2-yl)-2-chloro-4-methoxy-5-(5 -(((R)-1-(p-tolyl)ethyl)amino)methyl)furan-2-yl)benzamide
SMILES Kodhi:
ClC(C(C(N[C@H])(CC1=CC=C(C#N)C=C1)CN[C@@H]2CC[C@H](N)CC2)=O)=C3 )=CC(OC)=C3C(O4)=CC=C4CN[C@H](C)C5=CC=C(C)C=C5
InChi Code:
InChI=1S/C38H44ClN5O3/c1-24-4-10-28(11-5-24)25(2)42-23-32-16-17-36(47-32)34-19-33(35( 39)20-37(34)46-3)38(45)44-31(18-26-6-8-27(21-40)9-7-26)22-43-30-14-12- 29(41)13-15-30/h4-11,16-17,19-20,25,29-31,42-43H,12-15,18,22-23,41H2,1-3H3,(H ,44,45)/t25-,29-,30+,31-/m1/s1
InChi Key:
BSISGUIVBKDTQO-QIKYYPRYSA-N
Keyword:
BAY-850; BAY850; BAY 850
Solubility:DMSO
Kuchengeta:
Tsanangudzo:
"BAY-850 ichemical probe yeATAD2A bromodomain iyo inobvisa acetylated H4 peptide kubva kuATAD2 bromodomain ine IC50 kukosha kwe20 nM (HTRF). MST uye BROMOscan zviyero zvinoratidza Kd ye84.9 nM uye 120 nM, BAY- zvichiteerana. 850 inoratidza kusarudzwa kwakanaka pamusoro pemamwe ese mabromodomain (hapana hits muBROMOscan pa10 µM) uye inobvisa yakazara-yakareba ATAD2 kubva kuchromatin mumaseru mhenyu pamwero we 1 µM sekutsanangurwa kwazvinoitwa neFRAP Kudzivirira zvingangoitika zvisingatarisirwi zvinokonzeresa ≥ 5 µM haina kukurudzirwa (http://www.thesgc.org/chemical-probes/BAY-850) "
Chinangwa: makemikari probe yeATAD2A bromodomain
