BAY598 R-isomer
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 50mg | mudura | Wana quote |
| 250mg | mudura | Wana quote |
| 500mg | mudura | Wana quote |
Chemical Name:
(R,E)-N-(1-(N'-cyano-N-(3-(difluoromethoxy)phenyl)carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol- 4-yl)-N-ethyl-2-hydroxyacetamide
SMILES Kodhi:
CCN([C@@H]1CN(N=C1C2=CC(Cl)=C(C=C2)Cl)/C(NC3=CC=CC(OC(F)F)=C3)=N/C# N)C(CO)=O
InChi Code:
InChI=1S/C22H20Cl2F2N6O3/c1-2-31(19(34)11-33)18-10-32(30-20(18)13-6-7-16(23)17(24)8-13) 22(28-12-27)29-14-4-3-5-15(9-14)35-21(25)26/h3-9,18,21,33H,2,10-11H2,1H3, (H,28,29)/t18-/m1/s1
InChi Key:
OTTJIRVZJJGFTK-GOSISDBHSA-N
Keyword:
BAY-598 R-isomer; BAY 598 R-isomer; BAY598 R-isomer
Solubility:DMSO
Kuchengeta:
Tsanangudzo:
BAY-598 R-isomer ndiyo R-isomer yeBAY589. BAY-598 R-isomer inogona kushandiswa sechinhu chinongedzo. BAY-598 ine simba, peptide-inokwikwidza kemikari probe ye SMYD2. BAY-598 ine yakasarudzika chemotype inoenderana neyazvino SMYD2 kemikari probe LLY-507. BAY-598 inhibits in vitro methylation yep53K370 ine IC50 = 27 nM uye ine zvinopfuura 100-fold selectivity pane mamwe histone methyltransferases uye zvimwe zvisiri epigenetic zvinangwa. BAY-598 inhibits the methylation yep53K370 mumaseru ane IC50.<1 µM. (Kuenderera mberi neizvi, BAY-598 ine zvivakwa zvinofambirana nezviyedzo zve vivo.) Mushonga wekutonga, BAY-369, wakagadzirwawo. BAY-369 inhibits iyo in vitro methylation yep53K370 ine IC50 >70 micromolar.
Chinangwa:
