Chenodeoxycholic Acid

Chemical Name:

(R) -4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl Pentanoic acid

SMILES Kodhi:

C[C@@H]([C@H]1CC[C@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

InChi Code:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

InChi Key:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Keyword:

474-25-9, CAS:474-25-9，CAS：474-25-9，Chenodeoxycholic Acid, Anthropodeoxycholic acid,Anthropodesoxycholic acid,CCRIS 2195，Chendol,chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Solubility:Soluble muDMSO, kwete mumvura

Kuchengeta:Yakaoma, yakasviba uye pa 0 - 4 C kwenguva pfupi (mazuva kusvika kumavhiki) kana -20 C kwenguva refu (mwedzi kusvika kumakore)

Tsanangudzo:

Chenodiol, inozivikanwawo seChenodeoxycholic Acid uye chenocholic acid, inonzi bile acid. Inoitika sechinhu chichena chekristaro chisinganyungudika mumvura asi chinonyungudika mudoro uye acetic acid, ine nzvimbo yekunyungudika pa165-167 ° C. Minyu yeiyi carboxylic acid inonzi chenodeoxycholates. Chenodeoxycholic acid yakashandiswa sekurapa kwekunyungudutsa gallstones. Chenodeoxycholic acid inogona kushandiswa pakurapa cerebrotendineous xanthomatosis. Kambani yekuAustralia yebiotechnology yeGiaconda yakaedza marapirwo echirwere cheHepatitis C chinosanganisa chenodeoxycholic acid nebezafibrate.

Chinangwa: Yakashandiswa nyukireya receptor FXR