BAY 61-3606 2HCl
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 1g | Mudura | 1200 |
| 10g | Mudura | 5000 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
2-[[7-(3,4-Dimethoxyphenyl) imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide dihydrochloride
SMILES Kodhi:
O=C(N)C1=C(NC2=NC(C3=CC=C(OC)C(OC)=C3)=CC4=NC=CN24)N=CC=C1.[H]Cl.[H] Cl
InChi Code:
InChI=1S/C20H18N6O3.2ClH/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20 (24-14)25-19-13(18(21)27)4-3-7-23-19;;/h3-11H,1-2H3,(H2,21,27)(H,23,24) ,25);2*1H
InChi Key:
SPMFELFGGPQLN-UHFFFAOYSA-N
Keyword:
BAY 61-3606, 648903-57-5, BAY 613606, BAY-613606, BAY-61-3606
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)
Tsanangudzo:
BAY 61-3606 ine simba (Ki = 7.5 nM) uye inosarudza inhibitor yeSyk kinase. BAY 61-3606 inhibited kwete chete degranulation (IC50 kukosha pakati pe5 ne46 nM) asiwo lipid murevereri uye cytokine synthesis mumasero mast. BAY 61-3606 yainyanya kushanda mumabasophils akawanikwa kubva kune vanhu vane hutano zvidzidzo (IC50 = 10 nM) uye inoratidzika kunge ine simba mubasophils inowanikwa kubva kune atopic (yakakwirira serum IgE) zvidzidzo (IC50 = 8.1 nM). B cell receptor activation uye receptors yeFc chikamu cheIgG chiratidzo mune eosinophils uye monocytes zvakare akadzvinyirirwa zvine simba neBAY 61-3606.
Chinangwa: Syk
