Verucerfont

Verucerfont
  • Igoa:Verucerfont; GSK561679; NBI77860
  • Numera fa'amaumauga:CPDD1230
  • Numera CAS:885220-61-1
  • Molecular Weight:406.49
  • Fua Fa'atatau ole vaila'au:C22H26N6O2
  • Mo na'o su'esu'ega fa'asaienisi, ae le mo gasegase.

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    Igoa vaila'au:

    (S) -3-(4-methoxy-2-methylphenyl) -2,5-dimethyl-N-(1-(3-methyl-1,2,4-oxadiazol-5-yl) propyl)pyrazolo[1, 5-a] pyrimidin-7-amine

    SMILES Code:

    CC[C@H](NC1=CC(C)=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN12)C4=NC(C)=NO4

    InChi Code:

    InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14) (4)26-28(19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/ s1

    InChi Key:

    VKHVAUKFLBBZFJ-SFHVURJKSA-N

    upu autu:

    Verucerfont, GSK561679, GSK 561679, GSK-561679, NBI77860, NBI 77860, NBI-77860, 885220-61-1

    Solubility:Solu i le DMSO

    Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), poo le -20°C mo taimi uumi (masina).

    Fa'amatalaga:

    "Verucerfont, lea e lauiloa foi o le GSK561679 ma le NBI77860, o se CRF-1 antagonist. Verucerfont poloka le CRH-1 receptor, ma faʻaitiitia ai le faʻamalolo o le ACTH pe a maeʻa le faʻalavelave masani. o se mea e lua i le atinaʻeina o le ava malosi ma le toe faʻaleleia o le ava malosi Ua faʻaalia iʻuga manuia i suʻesuʻega manu ae leʻi faʻataʻitaʻiina tagata."

    Sini: CRF-1


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