LOXO-305;LY 3527727;Pirtobrutinib

LOXO-305;LY 3527727;Pirtobrutinib
  • Igoa:(S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- carboxamide
  • Numera fa'amaumauga:CPD108261
  • Numera CAS:2101700-15-4
  • Molecular Weight:479.43
  • Fua Fa'atatau ole vaila'au:C22 H21 F4 N5 O3
  • Mo na'o su'esu'ega fa'asaienisi, ae le mo gasegase.

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    Igoa vaila'au:

    (S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- carboxamide

    SMILES Code:

    O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC )=O)C=C2)N

    InChi Code:

    InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6- 13)10-29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32 )(H,29,33)/t11-/m0/s1

    InChi Key:

    FWZAWAUZXYCBKZ-NSHDSACASA-N

    upu autu:

    2101700-15 -4

    Solubility: 

    Teuina:Mago, pogisa ma i le 0 - 4 C mo taimi pupuu (aso i vaiaso) po'o le -20 C mo taimi uumi (masina i tausaga).

    Fa'amatalaga:

    Pirtobrutinib (LOXO-305) o se mea e sili ona filifilia ma e le o se faʻaogaina o le isi augatupulaga BTK inhibitor e mafai ona faʻalavelaveina suiga eseese o le BTK C481.

    Sini: BTK




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