AZD0780;EX-A6975;laroprovstatum; laroprovstat
Fa'amatalaga Oloa
Faailoga o oloa
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Igoa vaila'au:
6'-(((1S,3S)-3-((5-(difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-tasi
SMILES Code:
O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2
InChi Code:
InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10-23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26 )(H,24,25,27)/t13-,14-/m0/s1
InChi Key:
NCHUWRLOTSAFFN-KBPBESRZSA-N
upu autu:
2455427-91-3；CAS：2455427-91-3；CAS:2455427-91-3；AZD0780; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat
Solubility:
Teuina:Mago, pogisa ma i le 0 -4 C mo taimi pupuu (aso i vaiaso) po'o le -20 C mo taimi umi (masina i tausaga).
Fa'amatalaga:
PCSK9-IN-12 o se faʻalapotopotoga heteroaromatic. PCSK9-IN-12 o loʻo i ai le sootaga vavalalata mo PCSK9 ma le tau Kd<200 nM. PCSK9-IN-12 e mafai ona faʻaaogaina mo le suʻesuʻeina o le cholesterol metabolism.
Sini: PCSK9
