NST-628

Igoa vaila'au:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one

SMILES Code:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC))(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

InChi Code:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26) ,28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

upu autu:

3002056-30-3；CAS:3002056-30-3；CAS:3002056-30-3；NST-628；NST628；NST 628

Solubility: 

Teuina:Mago, pogisa ma i le 0 -4 C mo taimi pupuu (aso i vaiaso) po'o le -20 C mo taimi umi (masina i tausaga).

Fa'amatalaga:

O le NST-628 o le MAPK molecular gel mole faʻatasi ma le faʻaogaina o le paʻu toto-faiʻai, lea e mafai ona faʻalavelaveina le phosphorylation RAF ma le faʻagaoioia MEK.

Sini: RAF phosphorylation ma MEK