AZD4547

AZD4547
  • Igoa:AZD4547
  • Numera fa'amaumauga:CPDB0053
  • Numera CAS:1035270-39-3
  • Molecular Weight:463.6
  • Fua Fa'atatau ole vaila'au:C26H33N5O3
  • Mo na'o su'esu'ega fa'asaienisi, ae le mo gasegase.

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    Igoa vaila'au:

    N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide

    SMILES Code:

    O=C(NC1=NNC(CCC2=CC(OC)=CC(OC)=C2)=C1)C3=CC=C(N4C[C@H](C)N[C@H](C)C4 )C=C3

    InChi Code:

    InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21( 29-30-25)8-5 -19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,( H2,28,29,30,32)/t17-,18+

    InChi Key:

    VRQMAABPASPXMW-HDICACEKSA-N

    upu autu:

    AZD4547, AZD-4547, AZD 4547, 1035270-39-3

    Solubility:Solu i le DMSO

    Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), po'o le -20°C mo taimi uumi (masina)

    Fa'amatalaga:

    AZD 4547 o se faʻaiʻuga filifilia o le fibroblast growth factor receptor (FGFR) tyrosine kinase faʻatasi ai ma IC50 tau o 0.2, 2.5, ma 1.8 nM mo FGFR1, 2, ma le 3, faasologa.

    Sini: FGFR


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