DEL-22379

Izina ryimiti:

(Z) -N- (3 - (((5

Kode ya SMILES:

O = C (NC1 = CC2 = C (NC (/ C2 = C / C3 = CNC4 = C3C = C (OC) C = C4) = O) C = C1) CCN5CCCCC5

InChi Code:

InChI = 1S / C26H28N4O3 / c1-33-19-6-8-23-20 (15-19) 17 (16-27-23) 13-22-21-14-18 (5-7-24 (21) 29-26 (22) 32) 28-25 (31) 9-12-30-10-3-2-4-11-30 / h5-8,13-16,27H, 2-4,9-12H2, 1H3, (H, 28,31) (H, 29,32) / b22-13 +

InChi Urufunguzo:

INQUULPXCZAKMS-LPYMAVHISA-N

Ijambo ryibanze:

DEL-22379, DEL22379, DEL 22379, 181223-80-3

Gukemura:Gukemura muri DMSO

Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)

Ibisobanuro:

DEL-22379 ninzitizi ikomeye kandi ihitamo ERK Dimerization inhibitor. DEL-22379 ibuza ERK Dimerisation itagize ingaruka kuri fosifori ya ERK, ishyamba rya tumorigenez iterwa na RAS-ERK inzira ya oncogene. Hafi ya 50% yindwara mbi zabantu zerekana ibimenyetso RAS-ERK itagengwa; kubuza ni ingamba zemewe zo kwivanga antineoplastique.

Intego: ERK