AMG-510

AMG-510
  • Izina:AMG-510
  • Cataloge No.:CPD2809
  • CAS No.:2296729-00-3 ,( 2252403-56-6 umunyamoko)
  • Uburemere bwa molekile:560.23
  • Imiti yimiti:C30H30F2N6O3
  • Kubushakashatsi bwa siyansi gusa, ntabwo kubarwayi.

    Ibicuruzwa birambuye

    Ibicuruzwa

    Ingano Kuboneka Igiciro (USD)
    1g mu bubiko 1300
    5g mu bubiko 6000
    10g mu bubiko 10500

    Izina ryimiti:

    4 - ((S) -4-acryloyl-2-methylpiperazin-1-yl) -6-fluoro-7- (2-fluoro-6-hydroxyphenyl) -1- (2-isopropyl-4-methylpyridin-3-yl ) pyrido [2,3-d] pyrimidin-2 (1H) -umuntu

    Kode ya SMILES:

    O = C (C = C) N1C [C @ H] (C) N (C2 = NC (N (C3 = C (C) C = CN = C3C (C) C) C4 = C2C = C (F) C (C5 = C (O) C = CC = C5F) = N4) = O) CC1

    InChi Code:

    InChI = 1S / C30H30F2N6O3 / c1-6-23 (40) 36-12-13-37 (18 (5) 15-36) 28-19-14-21 (32) 26 (24-20 (31) 8- 7-9-22 (24) 39) 34 -29 (19) 38 (30 (41) 35-28) 27-17 (4) 10-11-33-25 (27) 16 (2) 3 / h6-11,14,16,18,39H, 1 , 12-13,15H2,2-5H3 / t18- / m0 / s1

    InChi Urufunguzo:

    NXQKSXLFSAEQCZ-SFHVURJKSA-N

    Ijambo ryibanze:

    AMG-510; AMG 510; AMG510

    Gukemura: 

    Ububiko: 

    Ibisobanuro:

    AMG-510 nimbaraga zikomeye za KRAS G12C. AMG-510 ihitamo intego ya KRAS p.G12C ihinduka, haba kurwego rwa ADN, RNA cyangwa proteine, kandi ikabuza, binyuze muburyo butarasobanurwa neza, kwerekana na / cyangwa selile yibibyimba byerekana binyuze muri mutant ya KRAS p.G12C. Ibi birashobora kubuza gukura muri KRAS p.G12C-yerekana ibibyimba

    Intego: KRAS


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