AMG-510
Ibicuruzwa birambuye
Ibicuruzwa
Ingano | Kuboneka | Igiciro (USD) |
1g | mu bubiko | 1300 |
5g | mu bubiko | 6000 |
10g | mu bubiko | 10500 |
Izina ryimiti:
4 - ((S) -4-acryloyl-2-methylpiperazin-1-yl) -6-fluoro-7- (2-fluoro-6-hydroxyphenyl) -1- (2-isopropyl-4-methylpyridin-3-yl ) pyrido [2,3-d] pyrimidin-2 (1H) -umuntu
Kode ya SMILES:
O = C (C = C) N1C [C @ H] (C) N (C2 = NC (N (C3 = C (C) C = CN = C3C (C) C) C4 = C2C = C (F) C (C5 = C (O) C = CC = C5F) = N4) = O) CC1
InChi Code:
InChI = 1S / C30H30F2N6O3 / c1-6-23 (40) 36-12-13-37 (18 (5) 15-36) 28-19-14-21 (32) 26 (24-20 (31) 8- 7-9-22 (24) 39) 34 -29 (19) 38 (30 (41) 35-28) 27-17 (4) 10-11-33-25 (27) 16 (2) 3 / h6-11,14,16,18,39H, 1 , 12-13,15H2,2-5H3 / t18- / m0 / s1
InChi Urufunguzo:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Ijambo ryibanze:
AMG-510; AMG 510; AMG510
Gukemura:
Ububiko:
Ibisobanuro:
AMG-510 nimbaraga zikomeye za KRAS G12C. AMG-510 ihitamo intego ya KRAS p.G12C ihinduka, haba kurwego rwa ADN, RNA cyangwa proteine, kandi ikabuza, binyuze muburyo butarasobanurwa neza, kwerekana na / cyangwa selile yibibyimba byerekana binyuze muri mutant ya KRAS p.G12C. Ibi birashobora kubuza gukura muri KRAS p.G12C-yerekana ibibyimba
Intego: KRAS