Ozanimod

Dzina la Chemical:

(S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2 - isopropoxybenzonitrile

SMILES Kodi:

N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

InChi kodi:

InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3- 4 -18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1-2H3 /t20-/m0/s1

InChi Key:

XRVDGNKRPOAQTN-FQEVSTJZSA-N

Mawu ofunika:

Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

Kusungunuka:Zosungunuka mu DMSO

Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).

Kufotokozera:

Ozanimod ndi yosankha, yopezeka pakamwa modulator ya sphingosine-1-phosphate (S1P) receptors S1P1 ndi SIP5. Zimapangitsa kuti S1P1 ilowe mkati, imachepetsa kuyendayenda kwa B ndi CCR7 (+) T lymphocytes, ndipo imachepetsa kutupa ndi zizindikiro za matenda mu zitsanzo zitatu za matenda a autoimmune.1 Ozanimod ali m'mayesero achipatala kuti abwererenso multiple sclerosis ndi ulcerative colitis.

Zolinga: S1P