STING agonist-4

Isem Kimiku:

1,1'-(butan-1,4-diyl)bis(2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazole-5-carboxamide)

Kodiċi SMILES:

O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC) (C)=NN6CC)=O)=NC2=C1)N

Kodiċi InChi:

InChI=1S/C34H38N12O4/c1-5-45-27(15-19(3)41-45)31(49)39-33-37-23-17-21(29(35)47)9-11- 25(23)43(33)13-7-8-14-44-26-12-10-22(30(36)48)18-24(26)38-34(44)40-32(50) 28-16-20(4)42-46(28)6-2/h9-12,15-18H,5-8,13-14H2,1-4H3,(H2,35,47)(H2,36, 48)(H,37,39,49)(H,38,40,50)

InChi Key:

ICZSAXDKFXTSGL-UHFFFAOYSA-N

Keyword:

Solubilità: 

Ħażna: 

Deskrizzjoni:

STING agonist-4 huwa stimulatur ta 'Interferon Genes (STING) agonist tar-riċettur b'kostanti inibitorja apparenti (IC50) ta' 20 nM. STING agonist-4 huwa kompost ibbażat fuq żewġ amidobenzimidazole (ABZI) relatat mas-simetrija biex joħloq ABZIs marbuta (diABZIs) b'rabta msaħħa ma' STING u funzjoni ċellulari.

Mira: STING