Asid Chenodeoxycholic

Nama Kimia:

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl )asid pentanoik

Kod SMILES:

Kod InChi:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Kunci InChi:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Kata kunci:

474-25-9，CAS:474-25-9，CAS：474-25-9，Asid Chenodeoxycholic，Asid antropodeoksikolik，Asid antropodesoksikolik，CCRIS 2195，Chendol，asid chenic; Chenix，Asid Chenodeoxycholic，Asid Chenodesoxycholic，Chenodiol，Asid Gallodesoxycholic， NSC 657949， Xenbilox

Keterlarutan:Larut dalam DMSO, bukan dalam air

Storan:Kering, gelap dan pada 0 - 4 C untuk jangka pendek (hari hingga minggu) atau -20 C untuk jangka panjang (bulan hingga tahun)

Penerangan:

Chenodiol, also known as Chenodeoxycholic Acid and chenocholic acid, is a bile acid. Ia berlaku sebagai bahan kristal putih yang tidak larut dalam air tetapi larut dalam alkohol dan asid asetik, dengan takat lebur pada 165-167 °C. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid has been used as medical therapy to dissolve gallstones. Chenodeoxycholic acid can be used in the treatment of cerebrotendineous xanthomatosis. The Australian biotechnology company Giaconda has tested a treatment for Hepatitis C infection that combines chenodeoxycholic acid with bezafibrate.

Sasaran: Reseptor nuklear diaktifkan FXR