MDK7526 HCl

MDK7526 HCl
  • Ingoa:MDK7526 HCl; Whakaheke pūmua 1 hydrochloride
  • Nama Putumōhio:CPDB1584
  • Nama CAS:1448189-80-7
  • Taumaha rāpoi:467.025
  • Tātai matū:C22H31ClN4O3S
  • Mo nga rangahau pūtaiao anake, kaua mo nga turoro.

    Taipitopito Hua

    Tohu Hua

    Rahi o te kete Te waatea Utu (USD)
    100mg Kei roto i nga taonga 500
    500mg Kei roto i nga taonga 800
    1g Kei roto i nga taonga 1200
    Ētahi atu Rahi Tikina Nga Korero Tikina Nga Korero

    Ingoa matū:

    (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

    Waehere SMILES:

    O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C (C3=C(C)N=CS3)C=C2.[H]Cl

    Waehere InChi:

    InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16( 27)11-26(17)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,( H,24,28);1H/t16-,17+,19-;/m1./s1

    Kī InChi:

    JYRTWGCWUBURGU-MSSRUXLCSA-N

    Kupumatua:

    MDK7526 HCl, Pūmua whakaheke 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

    Wairewa:Wairewa i roto i te DMSO

    Rokiroki:0 - 4°C mo te wa poto (ra ki nga wiki), -20°C ranei mo te wa roa (marama).

    Whakaahuatanga:

    MDK7526, e mohiotia ana ko VHL Ligand 1; Ko te whakakino pūmua 1, he kaha me te whiriwhiri i te whakaheke pūmua. Kei a MDK7526 he CAS#1448297-52-6, ko tana tote HCl he CAS#1448189-80-7. Ko te MDK7526 ka whai hua mo te whakahekenga o te kaiwhakawhiwhi androgen. Ka herea e te MDK7526 te kaikawe androgen kia noho tata ki te ubiquitin ligase kia pai ai te degrdn. (me te aukati) o te kaiwhakawhiwhi androgen.

    Whāinga: Androgen Receptor


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