LOXO-305;LY 3527727;Pirtobrutinib
Taipitopito Hua
Tohu Hua
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Ingoa matū:
(S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- carboxamide
Waehere SMILES:
O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC )=O)C=C2)N
Waehere InChi:
InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6- 13)10 -29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32)(H ,29,33)/t11-/m0/s1
Kī InChi:
FWZAWAUZXYCBKZ-NSHDSACASA-N
Kupumatua:
2101700-15-4；CAS:2101700-15-4；CAS:2101700-15-4；LOXO-305；LOXO 305；LOXO305；LY 3527727；LY-3527727；LY3527727；Pirtobrutinib
Wairewa:
Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).
Whakaahuatanga:
Ko te Pirtobrutinib (LOXO-305) he tino whiriwhiri me te kore covalent muri-whakatupuranga aukati BTK e taea tautāwhi i ngā rerekētanga whakakapinga BTK C481.
Whāinga: BTK
