GSK547

Ingoa matū:

(S)-6-(4-(5-(3,5-difluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbonyl)piperidin-1-yl)pirimidine-4-carbonitrile

Waehere SMILES:

N#CC1=NC=NC(N2CCC(C(N3N=CC[C@H]3C4=CC(F)=CC(F)=C4)=O)CC2)=C1

Waehere InChi:

InChI=1S/C20H18F2N6O/c21-15-7-14(8-16(22)9-15)18-1-4-26-28(18)20(29)13-2-5- 27(6-3-13)19-10-17(11-23)24-12-25-19/h4,7-10,12-13,18H,1-3,5-6H2/t18-/m0 /s1

Kī InChi:

SJVGFKBLUYAEOK-SFHVURJKSA-N

Kupumatua:

GSK547, GSK-547, GSK 547, RIP1i

Wairewa: 

Rokiroki: 

Whakaahuatanga:

Ko te GSK547 he tino whiriwhiri me te kaha te aukati o te RIP1 kinase e aro ana ki te RIP1 i roto i te vivo

Whāinga: RIP1