BAZ2-ICR
Taipitopito Hua
Tohu Hua
| Rahi o te kete | Te waatea | Utu (USD) |
| 100mg | Kei roto i nga taonga | 500 |
| 500mg | Kei roto i nga taonga | 800 |
| 1g | Kei roto i nga taonga | 1200 |
| Ētahi atu Rahi | Tikina Nga Korero | Tikina Nga Korero |
Ingoa matū:
4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile
Waehere SMILES:
CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2
Waehere InChi:
InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24 -26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
Kī InChi:
RRZVGDGTWNQAPW-UHFFFAOYSA-N
Kupumatua:
BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7
Wairewa:Wairewa i roto i te DMSO
Rokiroki:0 - 4°C mo te wa poto (ra ki nga wiki), -20°C ranei mo te wa roa (marama).
Whakaahuatanga:
Ko te BAZ2-ICR he rangahau matū tino pai mo nga rangahau mahi o te BAZ2 bromodomains in vitro me in vivo. Ko te bromodomain kei roto nga pūmua BAZ2A/B e whai waahi nui ana ki te whakahou i te chromatin me te whakarite ture mo nga RNA kore-waehere. Kei a BAZ2-ICR te IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; wairewa 25 mM (D2O) me F = 70%.
Whāinga: BAZ2