AZD0780;EX-A6975;laroprovstatum; laroprovstat

Ingoa matū:

6'-(((1S,3S)-3-((5-(difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-one

Waehere SMILES:

O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2

Waehere InChi:

InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10-23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26 )(H,24,25,27)/t13-,14-/m0/s1

Kī InChi:

NCHUWRLOTSAFFN-KBPBESRZSA-N

Kupumatua:

2455427-91-3；CAS:2455427-91-3；CAS:2455427-91-3；AZD0780; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat

Wairewa: 

Rokiroki:He maroke, he pouri me te 0 -4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).

Whakaahuatanga:

Ko te PCSK9-IN-12 he pūhui heteroaromatic. Ko te PCSK9-IN-12 he hononga hono mo PCSK9 me te uara Kd<200 nM. Ka taea te whakamahi PCSK9-IN-12 mo te ako o te cholesterol metabolism.

Whainga: PCSK9