Divarasib,GDC 6036

Divarasib,GDC 6036
  • Ingoa:1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one
  • Nama Putumōhio:CPD112857
  • Nama CAS:2417987-45-0
  • Taumaha rāpoi:622.06
  • Tātai matū:C29 H32 Cl F4 N7 O2
  • Mo nga rangahau pūtaiao anake, kaua mo nga turoro.

    Taipitopito Hua

    Tohu Hua

    Rahi o te kete Te waatea Utu (USD)
    0.1G Kei roto i nga taonga 550
    0.5G Kei roto i nga taonga 860
    1G Kei roto i nga taonga 1250

    Ingoa matū:

    1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one

    Waehere SMILES:

    NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F

    Waehere InChi:

    InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32), 33)34)15(2)11-20 (35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H ,1,6-10,13-14H2,2-4H3,(H2,35,36)

    Kī InChi:

    ZRBPIAWWRPFDPY-UHFFFAOYSA-N

    Kupumatua:

    2417987-45-0;CAS:2417987-45-0;CAS:2417987-45-0;Divarasib;GDC 6036

    Wairewa:WairewaKa whakatauhia

    Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).

    Whakaahuatanga:

    Ko te Divarasib (GDC-6036) he aukati KRAS G12C me te koiora o te waha me te whiriwhiringa.

    Whāinga: KRAS G12C aukati




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